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CAS 83777-68-8
(2R)-2-Amino-2-(2-chlorophenyl)cyclohexan-1-one hydrogen chloride
Codes: (XV)270899-2-c
Application context (from source-drug indications)
Major depressive disorderEsketamine HydrochlorideSuicidal ideationEsketamine HydrochlorideDepressive disorderEsketamine HydrochlorideAnaesthesiaEsketamine HydrochlorideTreatment-resistant depressionEsketamine HydrochloridePainEsketamine Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Esketamine Hydrochloride | Tier B — Position early | 2029 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(-)-2(S)-Amino-2-(2-chlorophenyl)cyclohexanone→2-(2-Chlorophenyl)-2-hydroxycyclohexan-1-one→2-Amino-2-(2-chlorophenyl)cyclohexanone→(2R)-2-Amino-2-(2-chlorophenyl)cyclohexan-1-one hydrogen chloride
Intermediates available on this site
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