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CAS 84392-32-5
4,4-dimethyl-2-(4'-methyl-[1,1'-biphenyl]-2-yl)-4,5-dihydrooxazole
Codes: IRBE-008
Application context (from source-drug indications)
HypertensionAtorvastatin Calcium Hydrate/IrbesartanHyperlipidaemiaAtorvastatin Calcium Hydrate/IrbesartanHypertensionIrbesartan/TrichlormethiazideOesophageal diseaseIrbesartanHypertensionIrbesartanDiabetic nephropathyIrbesartanHypercholesterolaemiaIrbesartanAlbuminuriaIrbesartanType 2 diabetesIrbesartan
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Atorvastatin Calcium Hydrate/Irbesartan | Tier C — Watch / trade | - |
| Irbesartan/Trichlormethiazide | Tier C — Watch / trade | - |
| Irbesartan | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
ethyl 1-aminocyclopentane-1-carboxylate→ethyl pentanimidate→2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one→4'-(bromomethyl)-[1,1'-biphenyl]-2-carbonitrile→4'-((2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile→2-(2-methoxyphenyl)-4,4-dimethyl-4,5-dihydrooxazole→p-tolylmagnesium bromide→4,4-dimethyl-2-(4'-methyl-[1,1'-biphenyl]-2-yl)-4,5-dihydrooxazole→4'-methyl-[1,1'-biphenyl]-2-carbonitrile
ethyl 1-aminocyclopentane-1-carboxylate→ethyl pentanimidate→2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one→4'-(bromomethyl)-[1,1'-biphenyl]-2-carbonitrile→4'-((2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile→2-(2-methoxyphenyl)-4,4-dimethyl-4,5-dihydrooxazole→p-tolylmagnesium bromide→4,4-dimethyl-2-(4'-methyl-[1,1'-biphenyl]-2-yl)-4,5-dihydrooxazole→4'-methyl-[1,1'-biphenyl]-2-carbonitrile
ethyl 1-aminocyclopentane-1-carboxylate→ethyl pentanimidate→2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one→4'-(bromomethyl)-[1,1'-biphenyl]-2-carbonitrile→4'-((2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile→2-(2-methoxyphenyl)-4,4-dimethyl-4,5-dihydrooxazole→p-tolylmagnesium bromide→4,4-dimethyl-2-(4'-methyl-[1,1'-biphenyl]-2-yl)-4,5-dihydrooxazole→4'-methyl-[1,1'-biphenyl]-2-carbonitrile
Intermediates available on this site
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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.