← Back to patent-cliff list
CAS 848133-88-0
(E)-N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide
Codes: NERT-004
Application context (from source-drug indications)
Breast cancerNeratinib Maleate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Neratinib Maleate | Tier C — Watch / trade | 2030 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-chloro-7-ethoxy-6-nitroquinoline-3-carbonitrile→6-amino-4-chloro-7-ethoxyquinoline-3-carbonitrile→(E)-4-(dimethylamino)but-2-enoyl chloride→(E)-N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide→3-chloro-4-(pyridin-2-ylmethoxy)aniline
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.