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CAS 85583-54-6

5-ethyl-2-(2-(4-nitrophenoxy)ethyl)pyridine

Codes: PIOG-003

Application context (from source-drug indications)

Type 2 diabetesAlogliptin Benzoate/Pioglitazone HydrochlorideType 2 diabetesPioglitazone HydrochloridePulmonary hypertensionPioglitazone HydrochlorideBreast cancerPioglitazone HydrochlorideNon-alcoholic steatohepatitisPioglitazone HydrochlorideCocaine addictionPioglitazone HydrochlorideAlcohol abusePioglitazone Hydrochloride

Source drugs (routes using this intermediate)

DrugTierExpiry
Alogliptin Benzoate/Pioglitazone HydrochlorideTier C — Watch / trade-
Pioglitazone HydrochlorideTier B — Position early-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Alogliptin Benzoate/Pioglitazone HydrochlorideOriginator routesteps: 5total yield: 20.50 g
2-(5-ethylpyridin-2-yl)ethan-1-ol→4-nitrophenol→5-ethyl-2-(2-(4-nitrophenoxy)ethyl)pyridine→4-(2-(5-ethylpyridin-2-yl)ethoxy)aniline→ethyl acrylate→ethyl 2-bromo-3-(4-(2-(5-ethylpyridin-2-yl)ethoxy)phenyl)propanoate→thiourea→5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)-4-iminothiazolidin-2-one
Pioglitazone HydrochlorideOriginator routesteps: 5total yield: 20.50 g
2-(5-ethylpyridin-2-yl)ethan-1-ol→4-nitrophenol→5-ethyl-2-(2-(4-nitrophenoxy)ethyl)pyridine→4-(2-(5-ethylpyridin-2-yl)ethoxy)aniline→ethyl acrylate→ethyl 2-bromo-3-(4-(2-(5-ethylpyridin-2-yl)ethoxy)phenyl)propanoate→thiourea→5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)-4-iminothiazolidin-2-one

Intermediates available on this site

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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.