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CAS 875318-41-5
2-(4-((((1-methyl-1H-indol-3-yl)methyl)amino)methyl)piperidin-1-yl)-N-((tetrahydro-2H-pyran-2-yl)oxy)pyrimidine-5-carboxamide
Codes: QUISIN-007
Application context (from source-drug indications)
葡萄膜黑素瘤Quisinostat HydrochlorideGlioblastomaQuisinostat HydrochloridePlasmodium infectionQuisinostat HydrochlorideMyelodysplastic syndromeQuisinostat HydrochlorideOvarian cancerQuisinostat HydrochlorideCutaneous T-cell lymphomaQuisinostat Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Quisinostat Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
O-(tetrahydro-2H-pyran-2-yl)hydroxylamine→2-(4-((((1-methyl-1H-indol-3-yl)methyl)amino)methyl)piperidin-1-yl)-N-((tetrahydro-2H-pyran-2-yl)oxy)pyrimidine-5-carboxamide→ethyl 2-(4-(aminomethyl)piperidin-1-yl)pyrimidine-5-carboxylate→1-methyl-1H-indole-3-carbaldehyde→(E)-ethyl 2-(4-((((1-methyl-1H-indol-3-yl)methylene)amino)methyl)piperidin-1-yl)pyrimidine-5-carboxylate→ethyl 2-(4-((((1-methyl-1H-indol-3-yl)methyl)amino)methyl)piperidin-1-yl)pyrimidine-5-carboxylate→sodium 2-(4-((((1-methyl-1H-indol-3-yl)methyl)amino)methyl)piperidin-1-yl)pyrimidine-5-carboxylate
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