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CAS 890708-68-6
5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonyl chloride
Codes: Tamsulosin Hydrochloride-043
Application context (from source-drug indications)
Erectile dysfunctionTadalafil/TamsulosinBenign prostatic hyperplasiaTadalafil/TamsulosinLower urinary tract symptomsSolifenacin Succinate/Tamsulosin HydrochlorideBenign prostatic hyperplasiaSolifenacin Succinate/Tamsulosin HydrochlorideOveractive bladderSolifenacin Succinate/Tamsulosin HydrochlorideDrug-related adverse effects and reactionsSolifenacin Succinate/Tamsulosin HydrochlorideBladder neck obstructionSolifenacin Succinate/Tamsulosin HydrochlorideBenign prostatic hyperplasiaDutasteride/Tamsulosin HydrochlorideBenign prostatic hyperplasiaTamsulosin HydrochlorideUrinary tract infectionTamsulosin HydrochlorideUrinary retentionTamsulosin HydrochlorideInguinal herniaTamsulosin HydrochlorideVoiding dysfunctionTamsulosin HydrochlorideLower urinary tract symptomsTamsulosin Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Tadalafil/Tamsulosin | Tier C — Watch / trade | - |
| Solifenacin Succinate/Tamsulosin Hydrochloride | Tier C — Watch / trade | - |
| Dutasteride/Tamsulosin Hydrochloride | Tier C — Watch / trade | - |
| Tamsulosin Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-(4-Methoxyphenyl)-2-propanone→(R)-(-)-1-Phenylethylamine→1-(4-Methoxyphenyl)-N-[1(R)-phenylethyl]propan-2(R)-amine→5-[(2R)-2-aminopropyl]-2-methoxybenzene-1-sulfonic acid→1-(2-Bromoethoxy)-2-ethoxybenzene→5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzene-1-sulfonic acid→5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonyl chloride
1-(4-Methoxyphenyl)-2-propanone→(R)-(-)-1-Phenylethylamine→1-(4-Methoxyphenyl)-N-[1(R)-phenylethyl]propan-2(R)-amine→5-[(2R)-2-aminopropyl]-2-methoxybenzene-1-sulfonic acid→1-(2-Bromoethoxy)-2-ethoxybenzene→5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzene-1-sulfonic acid→5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonyl chloride
1-(4-Methoxyphenyl)-2-propanone→(R)-(-)-1-Phenylethylamine→1-(4-Methoxyphenyl)-N-[1(R)-phenylethyl]propan-2(R)-amine→5-[(2R)-2-aminopropyl]-2-methoxybenzene-1-sulfonic acid→1-(2-Bromoethoxy)-2-ethoxybenzene→5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzene-1-sulfonic acid→5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonyl chloride
1-(4-Methoxyphenyl)-2-propanone→(R)-(-)-1-Phenylethylamine→1-(4-Methoxyphenyl)-N-[1(R)-phenylethyl]propan-2(R)-amine→5-[(2R)-2-aminopropyl]-2-methoxybenzene-1-sulfonic acid→1-(2-Bromoethoxy)-2-ethoxybenzene→5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzene-1-sulfonic acid→5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonyl chloride
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