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CAS 91175-93-8
(5'R,8'S,10'R,13'S,14'S)-5,5,13'-trimethyl-1',2',6',7',8',12',13',14',15',16'-decahydro-4'H,17'H-spiro[[1,3]dioxane-2,3'-[5,10]epoxycyclopenta[a]phenanthren]-17'-one
Codes: VILA-001
Application context (from source-drug indications)
子宫肿瘤VilaprisanLeiomyomaVilaprisanEndometriosisVilaprisan
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Vilaprisan | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(5'R,8'S,10'R,13'S,14'S)-5,5,13'-trimethyl-1',2',6',7',8',12',13',14',15',16'-decahydro-4'H,17'H-spiro[[1,3]dioxane-2,3'-[5,10]epoxycyclopenta[a]phenanthren]-17'-one→1,1,1,2,2-pentafluoro-2-iodoethane→(5'R,8'S,10'R,13'S,14'S,17'S)-5,5,13'-trimethyl-17'-(perfluoroethyl)-1',2',7',8',12',13',14',15',16',17'-decahydro-4'H,6'H-spiro[[1,3]dioxane-2,3'-[5,10]epoxycyclopenta[a]phenanthren]-17'-ol→(4-bromophenyl)(methyl)sulfane→(5R,8S,11R,13S,14S,17S)-5',5',13-trimethyl-11-(4-(methylthio)phenyl)-17-(perfluoroethyl)-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxane]-5,17(4H)-diol→(8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-11-(4-(methylsulfonyl)phenyl)-17-(perfluoroethyl)-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
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