← Back to patent-cliff list
CAS 912356-08-2
(3aS,12bS)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrol-1-one
Codes: ASEN-025
Application context (from source-drug indications)
SchizophreniaAsenapine MaleateManiaAsenapine MaleateBipolar I disorderAsenapine MaleateStutteringAsenapine MaleateParanoid schizophreniaAsenapine MaleateDisorganised schizophreniaAsenapine Maleate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Asenapine Maleate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
ethyl 4-(piperazin-1-yl)benzoate→(E)-1-bromo-2-(2-nitrovinyl)benzene→methyl 2-(5-chloro-2-methoxyphenyl)acetate→methyl 3-(2-bromophenyl)-2-(5-chloro-2-methoxyphenyl)-4-nitrobutanoate→4-(2-bromophenyl)-3-(5-chloro-2-methoxyphenyl)pyrrolidin-2-one→4-(2-bromophenyl)-3-(5-chloro-2-methoxyphenyl)-1-methylpyrrolidin-2-one→3-(2-bromophenyl)-2-(5-chloro-2-methoxyphenyl)-4-(methylamino)butanoic acid→(3S,4S)-4-(2-bromophenyl)-3-(5-chloro-2-methoxyphenyl)-1-methylpyrrolidin-2-one→(3S,4S)-4-(2-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1-methylpyrrolidin-2-one→(3aS,12bS)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrol-1-one
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.