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CAS 922-68-9
Methyl glyoxylateGlyoxylic acid methyl ester
Codes: Amoxicillin-001, (II)115092-7-a
Application context (from source-drug indications)
Helicobacter pylori infectionAmoxicillin/Omeprazole/RifabutinDyspepsiaAmoxicillin/Omeprazole/RifabutinDuodenal ulcerRabeprazole Sodium/Metronidazole/AmoxicillinImmune thrombocytopenic purpuraRabeprazole Sodium/Metronidazole/AmoxicillinGastric ulcerRabeprazole Sodium/Metronidazole/AmoxicillinGastritisRabeprazole Sodium/Metronidazole/AmoxicillinHelicobacter pylori infectionRabeprazole Sodium/Metronidazole/AmoxicillinMarginal zone B-cell lymphomaClarithromycin/Rabeprazole Sodium/AmoxicillinDuodenal ulcerClarithromycin/Rabeprazole Sodium/AmoxicillinImmune thrombocytopenic purpuraClarithromycin/Rabeprazole Sodium/AmoxicillinGastric ulcerClarithromycin/Rabeprazole Sodium/AmoxicillinGastritisClarithromycin/Rabeprazole Sodium/AmoxicillinHelicobacter pylori infectionClarithromycin/Rabeprazole Sodium/AmoxicillinGlaucomaProxodolol hydrochloride/Pilocarpine HydrochlorideBacterial infectionAmoxicillin Sodium闭角型青光眼Pilocarpine HydrochlorideOcular hypertensionPilocarpine HydrochlorideOpen-angle glaucomaPilocarpine Hydrochloride瞳孔缩小Pilocarpine HydrochlorideSjögren's syndromePilocarpine Hydrochloride虹膜炎Pilocarpine Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Amoxicillin/Omeprazole/Rifabutin | Tier C — Watch / trade | - |
| Rabeprazole Sodium/Metronidazole/Amoxicillin | Tier C — Watch / trade | - |
| Clarithromycin/Rabeprazole Sodium/Amoxicillin | Tier C — Watch / trade | - |
| Proxodolol hydrochloride/Pilocarpine Hydrochloride | Tier C — Watch / trade | - |
| Amoxicillin Sodium | Tier C — Watch / trade | - |
| Pilocarpine Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
Methyl glyoxylate→(S)-(-)-1-Phenylethylamine→(1S)-1-(2-Naphthyl)ethanamine→Methyl (2Z)-[[(1S)-1-phenylethyl]imino]acetate→Methyl (2Z)-[[(1S)-1-(naphthalen-2-yl)ethyl]imino]acetate→Carbolic acid→Methyl (2R)-(4-hydroxyphenyl)[(1-phenylethyl)amino]acetate→Methyl (2R)-(4-hydroxyphenyl)[[1-(naphthalen-2-yl)ethyl]amino]acetate→Methyl (2R)-(4-hydroxyphenyl)[(1-phenylethyl)amino]acetate hydrogen chloride (1/1)→Methyl (2R)-(4-hydroxyphenyl)[[1-(naphthalen-2-yl)ethyl]amino]acetate hydrogen chloride (1/1)→D-p-Hydroxyphenylglycine methyl ester hydrochloride→D-p-yHdroxyphenylglycine methyl ester→(+)-6-Aminopenicillanic acid
Methyl glyoxylate→(S)-(-)-1-Phenylethylamine→(1S)-1-(2-Naphthyl)ethanamine→Methyl (2Z)-[[(1S)-1-phenylethyl]imino]acetate→Methyl (2Z)-[[(1S)-1-(naphthalen-2-yl)ethyl]imino]acetate→Carbolic acid→Methyl (2R)-(4-hydroxyphenyl)[(1-phenylethyl)amino]acetate→Methyl (2R)-(4-hydroxyphenyl)[[1-(naphthalen-2-yl)ethyl]amino]acetate→Methyl (2R)-(4-hydroxyphenyl)[(1-phenylethyl)amino]acetate hydrogen chloride (1/1)→Methyl (2R)-(4-hydroxyphenyl)[[1-(naphthalen-2-yl)ethyl]amino]acetate hydrogen chloride (1/1)→D-p-Hydroxyphenylglycine methyl ester hydrochloride→D-p-yHdroxyphenylglycine methyl ester→(+)-6-Aminopenicillanic acid
Methyl glyoxylate→(S)-(-)-1-Phenylethylamine→(1S)-1-(2-Naphthyl)ethanamine→Methyl (2Z)-[[(1S)-1-phenylethyl]imino]acetate→Methyl (2Z)-[[(1S)-1-(naphthalen-2-yl)ethyl]imino]acetate→Carbolic acid→Methyl (2R)-(4-hydroxyphenyl)[(1-phenylethyl)amino]acetate→Methyl (2R)-(4-hydroxyphenyl)[[1-(naphthalen-2-yl)ethyl]amino]acetate→Methyl (2R)-(4-hydroxyphenyl)[(1-phenylethyl)amino]acetate hydrogen chloride (1/1)→Methyl (2R)-(4-hydroxyphenyl)[[1-(naphthalen-2-yl)ethyl]amino]acetate hydrogen chloride (1/1)→D-p-Hydroxyphenylglycine methyl ester hydrochloride→D-p-yHdroxyphenylglycine methyl ester→(+)-6-Aminopenicillanic acid
1-Butanone→Glyoxylic acid methyl ester→Methyl (2R,3S)-3-formyl-2-hydroxypentanoate→(2S,3R)-2-Ethyl-3-hydroxy-4-methoxy-4-oxobutanoic acid→Diethyl (2S,3R)-2-methyl-3-hydroxysuccinate→Dimethyl (2S,3R)-2-ethyl-3-[(4-methylbenzene-1-sulfonyl)oxy]butanedioate
Methyl glyoxylate→(S)-(-)-1-Phenylethylamine→(1S)-1-(2-Naphthyl)ethanamine→Methyl (2Z)-[[(1S)-1-phenylethyl]imino]acetate→Methyl (2Z)-[[(1S)-1-(naphthalen-2-yl)ethyl]imino]acetate→Carbolic acid→Methyl (2R)-(4-hydroxyphenyl)[(1-phenylethyl)amino]acetate→Methyl (2R)-(4-hydroxyphenyl)[[1-(naphthalen-2-yl)ethyl]amino]acetate→Methyl (2R)-(4-hydroxyphenyl)[(1-phenylethyl)amino]acetate hydrogen chloride (1/1)→Methyl (2R)-(4-hydroxyphenyl)[[1-(naphthalen-2-yl)ethyl]amino]acetate hydrogen chloride (1/1)→D-p-Hydroxyphenylglycine methyl ester hydrochloride→D-p-yHdroxyphenylglycine methyl ester→(+)-6-Aminopenicillanic acid
1-Butanone→Glyoxylic acid methyl ester→Methyl (2R,3S)-3-formyl-2-hydroxypentanoate→(2S,3R)-2-Ethyl-3-hydroxy-4-methoxy-4-oxobutanoic acid→Diethyl (2S,3R)-2-methyl-3-hydroxysuccinate→Dimethyl (2S,3R)-2-ethyl-3-[(4-methylbenzene-1-sulfonyl)oxy]butanedioate
Intermediates available on this site
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