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CAS 93413-78-6,99300-78-4
1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride
Codes: Desvenlafaxine-024
Application context (from source-drug indications)
Major depressive disorderDesvenlafaxineDepressive disorderDesvenlafaxine
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Desvenlafaxine | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-(1-Hydroxycyclohexyl)-2-(4-methoxyphenyl)acetonitrile→1-[2-Amino-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride→1-[2-Amino-1-(4-methoxyphenyl)ethyl]cyclohexanol→4-[2-Amino-1-(1-hydroxycyclohexyl)ethyl]phenol→4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol→1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol→1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride
2-(4-Methoxyphenyl)acetonitrile→Cyclohexanone→2-(1-Hydroxycyclohexyl)-2-(4-methoxyphenyl)acetonitrile→1-[2-Amino-1-(4-methoxyphenyl)ethyl]cyclohexanol→1-[2-Amino-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride→1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride→1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol→4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol→1-[2-(Dimethylamino)-1-[4-[(4-methoxybenzyl)oxy]phenyl]ethyl]cyclohexanol→1-{1-[4-(Benzyloxy)phenyl]-2-(dimethylamino)ethyl}cyclohexan-1-ol→Butanedioic acid 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol
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