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CAS 955401-37-3
tert-butyl 3-(((R)-3-hydroxy-1-methoxy-1-oxopropan-2-yl)carbamoyl)morpholine-4-carboxylate
Codes: Elinzanetant-002
Application context (from source-drug indications)
Hot flushesElinzanetantVasomotor symptomsElinzanetantHR阳性乳腺癌Elinzanetant睡眠障碍ElinzanetantMenopausal symptomsElinzanetantOpioid dependenceElinzanetant
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Elinzanetant | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-(tert-butoxycarbonyl)morpholine-3-carboxylic acid→tert-butyl 3-(((R)-3-hydroxy-1-methoxy-1-oxopropan-2-yl)carbamoyl)morpholine-4-carboxylate→(7R)-7-(hydroxymethyl)hexahydropyrazino[2,1-c][1,4]oxazine-6,9-dione→((7S)-octahydropyrazino[2,1-c][1,4]oxazin-7-yl)methanol→(7S,9aS)-7-(((tert-butyldimethylsilyl)oxy)methyl)octahydropyrazino[2,1-c][1,4]oxazine→2-(3,5-bis(trifluoromethyl)phenyl)-N-(6-chloro-4-(4-fluoro-2-methylphenyl)pyridin-3-yl)-N,2-dimethylpropanamide→2-(3,5-bis(trifluoromethyl)phenyl)-N-(6-((7S,9aS)-7-(((tert-butyldimethylsilyl)oxy)methyl)hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl)-4-(4-fluoro-2-methylphenyl)pyridin-3-yl)-N,2-dimethylpropanamide→tert-butyl (6-chloro-4-methylpyridin-3-yl)(methyl)carbamate→6-chloro-N,4-dimethylpyridin-3-amine→(4-fluoro-2-methylphenyl)boronic acid→6-chloro-4-(4-fluoro-2-methylphenyl)-N-methylpyridin-3-amine→2-(3,5-bis(trifluoromethyl)phenyl)-2-methylpropanoyl chloride
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | N-Boc-O-Benzyl-D-serine Pharmaceutical Intermediates | On request | On request | On request | — | |
| Qualified Partner — East China API Works | 6-chloro-4-(4-fluoro-2-methylphenyl)pyridin-3-amine hydrochloride Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Nantong cGMP Site | N-[6-Chloro-4-(4-fluoro-2-methylp henyl)-3-pyridinyl]-N,a,a-trimethy Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Taizhou GMP-like Site | 3-Morpholinemethanol, 4-(phenylmethyl)-, hydrochloride Pharmaceutical Intermediates | On request | On request | On request | — | |
| Qualified Partner — East China API Works | (7S,9aS)-7-((Benzyloxy)methyl)octahydropyrazino[2,1-c][1,4]oxazine dioxalate salt Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Nantong cGMP Site | 2-(3,5-bis(trifluoroMethyl)phenyl)-2-Methyl propanoic acid Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Taizhou GMP-like Site | ((7S)-octahydropyrazino[2,1-c][1,4]oxazin-7-yl)methanol Pharmaceutical Intermediates | On request | On request | On request | — | |
| Qualified Partner — East China API Works | 4-Boc-3-morpholinecarboxylic Acid Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Nantong cGMP Site | 2-(3,5-bis-trifluoromethylphenyl)-2-methyl-propionyl chloride Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.