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CAS 98071-16-0
1-Aminocyclobutanecarboxylic acid hydrochloride
Codes: (X)805433-1-a
Application context (from source-drug indications)
Idiopathic pulmonary fibrosisNerandomilastInterstitial lung diseaseNerandomilastPulmonary fibrosisNerandomilast肌炎NerandomilastSystemic sclerosisNerandomilast肌病Nerandomilast
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Nerandomilast | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-Mercaptoacetic acid methyl ester→2-Propenoic acid methyl ester→3-(Methoxycarbonylmethylthio)propionsauremethylester→2-Carbomethoxy-2,3,4,5-tetrahydrothiophen-3-one→Carbamide→3-Ureido-4,5-dihydro-thiophene-2-carboxylic acid methyl ester→6,7-Dihydrothieno[3,2-d]pyrimidine-2,4-diol→2,4-Dichloro-6,7-dihydrothieno[3,2-d]pyrimidine→(1-Aminocyclobutyl)methanol tosylate→(1-Aminocyclobutyl)methanol hydrogen chloride→1-Aminocyclobutanecarboxylic acid hydrochloride→[1-[(2-Chloro-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl)amino]cyclobutyl]methanol→(5R)-2-Chloro-4-[[1-(hydroxymethyl)cyclobutyl]amino]-6,7-dihydro-5H-5lambda4-thieno[3,2-d]pyrimidin-5-one→5-Chloro-2-(piperidin-4-yl)pyrimidine hydrogen chloride→4-Methylbenzene-1-sulfonic acid 5-chloro-2-(piperidin-4-yl)pyrimidine→5-Chloro-2-(piperidin-4-yl)pyrimidine sulfate→4-(5-Chloropyrimidin-2-yl)piperidin-1-ium hexafluoridophosphate(1-)→Piperidine-4-carboximidamide
Intermediates available on this site
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