2-Methyl-L-proline Methyl ester hydrochloride
Intermediate
IntermediateConfidentiality：Public
- INN / Generic Name
- 2-Methyl-L-proline Methyl ester hydrochloride
- CAS No.
- 220060-08-2
- Current Status
- Official intermediate catalog (API: Trofinetide)
- MOQ
- On request
- Lead Time
- On request
- Price Range
- On request
Formulation & registration fields (API/FDF oriented — tap to expand)
- Dosage Form
- —
- Strength
- —
- Therapy Area
- Pharmaceutical Intermediates
- Indication
- API: Trofinetide
- GMP Certification
- —
- CEP
- No
- DMF Type
- —
- Stability Data
- —
- BE Required
- Not required / waivable
- Registration Pathway
- FSO supply (non-registered substance)
HS Code
2922.491293 customs bills on file
Registrable Markets
Global
Process / Sequence / Exact Price
- Process Summary
- Intermediate #2 of Route 1 (5 steps) for Trofinetide. Route materials include: (S)-2-methylpyrrolidine-2-carboxylic acid, 2-(((benzyloxy)carbonyl)amino)acetic acid, methyl (S)-1-(((benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carboxylate, (S)-1-(((benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carboxylic acid, dibenzyl L-glutamate 4-methylbenzenesulfonate, dibenzyl ((S)-1-(((benzyloxy)carbonyl)glycyl)-2-methylpyrrolidine-2-carbonyl)-L-glutamate, Trofinetide. Source: Pharmacodia route data (in-house patent-cliff DB); full step sequence via SciFinder / Google Patents.Synthesis route auto-filled from in-house Pharmacodia route data — verify full steps on SciFinder / Google Patents.
- Exact Price