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Anticoagulation & Thrombosis
32 · drugs26 · with routes20 · with on-sale intermediates
32 patent-cliff drugs in Anticoagulation & Thrombosis (classified by indication keywords and explicit molecule lists from our structured data), 26 with recorded synthesis routes and 20 with on-sale intermediates. Every "Available" badge links to real listings for RFQ.
| Drug | Tier | Expiry | Indications | Routes | CAS count | Available |
|---|---|---|---|---|---|---|
| Ticagrelor | B · Position early | 2029 | Stroke, Acute coronary syndrome, Myocardial infarction | 5 | 55 | Available ×55 |
| Rivaroxaban | A · Act now | 2026 | Pulmonary embolism, Stroke, Congenital heart defect | 6 | 46 | Available ×46 |
| Dabigatran Etexilate Mesylate | B · Position early | - | Venous thromboembolism, Embolism, Stroke | 7 | 31 | Available ×31 |
| Apixaban | A · Act now | 2028 | Pulmonary embolism, Venous thrombosis, Paget-Schroetter syndrome | 7 | 30 | Available ×30 |
| Cangrelor Tetrasodium | C · Watch | - | Coronary thrombosis, Myocardial infarction, Thrombosis | 2 | 21 | Available ×21 |
| Avatrombopag Maleate | C · Watch | 2030 | Thrombocytopenia, Immune thrombocytopenic purpura, Liver disease | 1 | 11 | Available ×11 |
| Pacritinib Citrate | C · Watch | - | Myelofibrosis | 2 | 15 | Available ×7 |
| Fostamatinib disodium hexahydrate | C · Watch | - | Immune thrombocytopenic purpura, Thrombocytopenia | 1 | 6 | Available ×6 |
| Clarithromycin/Rabeprazole Sodium/Amoxicillin | C · Watch | - | Marginal zone B-cell lymphoma, Duodenal ulcer, Immune thrombocytopenic purpura | 20 | 46 | Available ×4 |
| Rabeprazole Sodium/Metronidazole/Amoxicillin | C · Watch | - | Duodenal ulcer, Immune thrombocytopenic purpura, Gastric ulcer | 13 | 39 | Available ×4 |
| Edoxaban Tosilate Hydrate | B · Position early | 2028 | Pulmonary embolism, Venous thromboembolism, Stroke | 6 | 37 | Available ×4 |
| Tirofiban Hydrochloride Hydrate | C · Watch | - | Unstable angina, Myocardial infarction, Coronary thrombosis | 2 | 21 | Available ×3 |
| Orelabrutinib | C · Watch | - | Marginal zone B-cell lymphoma, Mantle cell lymphoma, Chronic lymphocytic leukaemia | 3 | 20 | Available ×2 |
| Rosuvastatin Calcium | B · Position early | - | Homozygous familial hypercholesterolaemia, Heterozygous familial hypercholesterolaemia, Hyperlipoproteinaemia type III | 5 | 51 | Available ×1 |
| Anagrelide Hydrochloride Hydrate | C · Watch | - | Essential thrombocythaemia, Myeloproliferative neoplasm | 5 | 27 | Available ×1 |
| Ticlopidine Hydrochloride/Ginkgo Biloba Leaf Dried Extract | C · Watch | - | Arterial occlusive disease, Cerebrovascular disease, Embolism and thrombosis | 4 | 32 | Available ×1 |
| Ticlopidine Hydrochloride | C · Watch | - | Thromboembolism, Arterial occlusive disease, Transient ischaemic attack | 4 | 32 | Available ×1 |
| Macitentan | B · Position early | - | Pulmonary arterial hypertension | 2 | 18 | Available ×1 |
| Lusutrombopag | C · Watch | 2031 | Thrombocytopenia | 1 | 12 | Available ×1 |
| Chidamide | C · Watch | - | Diffuse large B-cell lymphoma, T-cell leukaemia, Breast cancer | 1 | 6 | Available ×1 |
| Fondaparinux Sodium | C · Watch | - | Pulmonary embolism, Venous thrombosis, Myocardial infarction | 5 | 43 | - |
| Betrixaban | C · Watch | 2028 | Venous thromboembolism, Hepatic function decline, Atrial fibrillation | 2 | 10 | - |
| Panobinostat Lactate | C · Watch | - | Multiple myeloma | 2 | 11 | - |
| Fedratinib | C · Watch | - | Myelofibrosis, Splenomegaly | 1 | 4 | - |
| Riociguat | B · Position early | - | Pulmonary arterial hypertension, Pulmonary hypertension, Chronic thromboembolic pulmonary hypertension | 1 | 10 | - |
| Bevifibatide Citrate | C · Watch | - | Acute coronary syndrome | 1 | 8 | - |
| Defibrotide sodium | C · Watch | - | Hepatic veno-occlusive disease | - | - | - |
| Clopidogrel Bisulfate/Aspirin | C · Watch | - | Atherosclerosis, Acute coronary syndrome, Thrombosis | - | - | - |
| Keverprazan Hydrochloride | C · Watch | - | Helicobacter pylori infection, Duodenal ulcer, Peptic oesophagitis | - | - | - |
| Dermatan sulfate | C · Watch | - | Venous thromboembolism, Thrombosis, Thrombocytopenia | - | - | - |
| Ardeparin | C · Watch | - | Pulmonary embolism, Venous thrombosis | - | - | - |
| Flonoltinib maleate | C · Watch | - | Myelofibrosis, 丝虫病, 红细胞增多症 | - | - | - |
Frequently asked questions
Which patent-cliff drugs in Anticoagulation & Thrombosis are worth tracking?
32 drugs related to Anticoagulation & Thrombosis are tracked on this site, 26 of them with recorded synthesis routes. See the table above and open each drug profile for routes and intermediates.
Where can I source Anticoagulation & Thrombosis intermediates?
Key intermediates of 20 drugs in this table are available through the Unibest supply network; for the rest, submit an RFQ per CAS on the intermediate profile pages.
Where can I check patent expiry for these drugs?
Each drug profile shows the public expiry year; yearly overviews are available at /patent-cliff/expires/<year>.
Source: cross-verified structured fields · Classification: indication keywords + explicit molecule lists · 2026-09-29