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CAS 290297-22-2
N-(4-iodo-6-(4-methylpiperazin-1-yl)pyridin-3-yl)pivalamide
Codes: NETUP-015
Application context (from source-drug indications)
Chemotherapy-induced nausea and vomitingNetupitantNeoplasmNetupitant
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Netupitant | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-chloro-5-nitropyridine→1-methyl-4-(5-nitropyridin-2-yl)piperazine→6-(4-methylpiperazin-1-yl)pyridin-3-amine→N-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)pivalamide→N-(4-iodo-6-(4-methylpiperazin-1-yl)pyridin-3-yl)pivalamide→o-tolylboronic acid→N-(6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)pivalamide→6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-amine
Intermediates available on this site
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