CAS 872-34-4

pyrrolidin-2-imine

Codes: TIPIRA-008

Application context (from source-drug indications)

Oesophageal cancerTipiracil HydrochlorideGastric cancerTipiracil HydrochlorideAdenocarcinomaTipiracil Hydrochloride

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Tipiracil Hydrochloride	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Tipiracil HydrochlorideOptimised routesteps: 2total yield: 2.68 g (Tipiracil)

5-chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dione→5-chloro-6-(chloromethyl)pyrimidine-2,4(1H,3H)-dione→6-(chloromethyl)pyrimidine-2,4(1H,3H)-dione→pyrrolidin-2-imine

Intermediates available on this site

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