Sebetralstat
Tier C — Watch / tradeSebetralstat
Targets：KLKB1
Brand：Ekterly
Indications (approved)：遗传性血管性水肿
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| Sebetralstat-001 | 16473-35-1 | (4-(chloromethyl)phenyl)methanol |
| Sebetralstat-002 | 1564668-60-5 | 1-(4-(hydroxymethyl)benzyl)pyridin-2(1H)-one |
| Sebetralstat-003 | 1801254-81-8 | 1-(4-(chloromethyl)benzyl)pyridin-2(1H)-one |
| Sebetralstat-004 | 318496-66-1 | methyl 3-(methoxymethyl)-1H-pyrazole-4-carboxylate |
| Sebetralstat-005 | - | methyl 3-(methoxymethyl)-1-(4-((2-oxopyridin-1(2H)-yl)methyl)benzyl)-1H-pyrazole-4-carboxylate |
| Sebetralstat-006 | - | methyl 5-(methoxymethyl)-1-(4-((2-oxopyridin-1(2H)-yl)methyl)benzyl)-1H-pyrazole-4-carboxylate |
| Sebetralstat-007 | - | 3-(methoxymethyl)-1-(4-((2-oxopyridin-1(2H)-yl)methyl)benzyl)-1H-pyrazole-4-carboxylic acid |
| Sebetralstat-008 | 1256812-75-5 | (3-fluoro-4-methoxypyridin-2-yl)methanamine |
Frequently asked questions
What are the approved indications of Sebetralstat?
Approved indications include: 遗传性血管性水肿.
When does the Sebetralstat patent expire?
No public expiry year is available for Sebetralstat yet; this page updates once verified.
How many synthesis routes are recorded for Sebetralstat?
1 synthesis routes are recorded; the shortest is 5 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Sebetralstat intermediates?
All intermediates in Sebetralstat routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Sebetralstat intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-22