Buloxibutid

Tier C — Watch / trade

Buloxibutid

Vicore Pharma

Originator

First approval

Expiry (public)

No sales data

Peak sales

Small molecule

Type

Targets：AT2

Indications (approved)：COVID-19, Idiopathic pulmonary fibrosis, 雷诺氏病, Systemic sclerosis

Regional status

Phase III

2021-09-16

Phase III

2021-09-16

China

Japan

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 7 · Total yield 57.8 mg (M-024)

M-024477775-14-7M-024-00116629-19-9M-024-002100342-30-1M-024-003146013-28-7M-024-004163520-14-7M-024-00572459-46-2M-024-006477775-35-2M-024-007477775-36-3M-024-008592-34-7M-024-009589-15-1API · Buloxibutid

Code	CAS No.	Intermediate
M-024	477775-14-7	butyl ((3-(4-((1H-imidazol-1-yl)methyl)phenyl)-5-isobutylthiophen-2-yl)sulfonyl)carbamate
M-024-001	16629-19-9	thiophene-2-sulfonyl chloride
M-024-002	100342-30-1	N-(tert-butyl)thiophene-2-sulfonamide
M-024-003	146013-28-7	N-(tert-butyl)-5-isobutylthiophene-2-sulfonamide
M-024-004	163520-14-7	(2-(N-(tert-butyl)sulfamoyl)-5-isobutylthiophen-3-yl)boronic acid
M-024-005	72459-46-2	1-(4-bromobenzyl)-1H-imidazole
M-024-006	477775-35-2	3-(4-((1H-imidazol-1-yl)methyl)phenyl)-N-(tert-butyl)-5-isobutylthiophene-2-sulfonamide
M-024-007	477775-36-3	3-(4-((1H-imidazol-1-yl)methyl)phenyl)-5-isobutylthiophene-2-sulfonamide
M-024-008	592-34-7	butyl carbonochloridate
M-024-009	589-15-1	1-bromo-4-(bromomethyl)benzene

Frequently asked questions

What are the approved indications of Buloxibutid?

Approved indications include: COVID-19, Idiopathic pulmonary fibrosis, 雷诺氏病, Systemic sclerosis.

When does the Buloxibutid patent expire?

No public expiry year is available for Buloxibutid yet; this page updates once verified.

How many synthesis routes are recorded for Buloxibutid?

1 synthesis routes are recorded; the shortest is 7 steps with 57.8 mg (M-024) total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Buloxibutid intermediates?

All intermediates in Buloxibutid routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Buloxibutid intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-06