Fosifloxuridine nafalbenamide
Tier C — Watch / tradeFosifloxuridine nafalbenamide
Targets：TYMS
Indications (approved)：Colorectal cancer, Non-small cell lung cancer, Melanoma, Hodgkin's disease, 间皮组织肿瘤, Squamous cell carcinoma, Urothelial carcinoma, 三阴性乳腺癌
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| NUC-3373 | 1332837-31-6 | benzyl ((((2R,3S,5R)-5-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methoxy)(naphthalen-1-yloxy)phosphoryl)-L-alaninate |
| NUC-3373-001 | 90-15-3 | naphthalen-1-ol |
| NUC-3373-002 | 31651-76-0 | naphthalen-1-yl phosphorodichloridate |
| NUC-3373-003 | 1832664-47-7 | benzyl L-alaninate 4-methylbenzenesulfonate |
| NUC-3373-004 | 906670-24-4 | benzyl (chloro(naphthalen-1-yloxy)phosphoryl)-L-alaninate |
| NUC-3373-005 | 50-91-9 | 5-fluoro-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione |
Frequently asked questions
What are the approved indications of Fosifloxuridine nafalbenamide?
Approved indications include: Colorectal cancer, Non-small cell lung cancer, Melanoma, Hodgkin's disease, 间皮组织肿瘤, Squamous cell carcinoma, Urothelial carcinoma, 三阴性乳腺癌.
When does the Fosifloxuridine nafalbenamide patent expire?
No public expiry year is available for Fosifloxuridine nafalbenamide yet; this page updates once verified.
How many synthesis routes are recorded for Fosifloxuridine nafalbenamide?
1 synthesis routes are recorded; the shortest is 3 steps with 47 mg (NUC-3373) total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Fosifloxuridine nafalbenamide intermediates?
All intermediates in Fosifloxuridine nafalbenamide routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Fosifloxuridine nafalbenamide intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-08