Sanfetrinem cilexetil

Tier C — Watch / trade

GSK

Originator

First approval

Expiry (public)

No sales data

Peak sales

Small molecule

Type

Targets：Not applicable

Indications (approved)：Mycobacterium tuberculosis infection, Pulmonary tuberculosis, Bacterial infection

Regional status

China

Japan

Synthetic routes & intermediates2 routes

Originator routes × 1Optimised (non-patent) × 1Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 12 · Total yield 0.16 g

SANFC-0017429-44-9SANFC-0021797-75-7SANFC-003181798-18-5SANFC-00476855-69-1SANFC-005188396-10-3SANFC-006188396-11-4SANFC-007—SANFC-008—SANFC-009135297-22-2SANFC-01035249-73-1SANFC-011181798-22-1SANFC-012181798-23-2SANFC-013135446-51-4SANFC-01469340-58-5SANFC-015—SANFC-016135502-34-0SANFC-01799464-83-2API · Sanfetrinem cilexetil

Code	CAS No.	Intermediate
SANFC-001	7429-44-9	2-methoxycyclohexan-1-one
SANFC-002	1797-75-7	diallyl malonate
SANFC-003	181798-18-5	allyl 3-methoxy-2-oxocyclohexane-1-carboxylate
SANFC-004	76855-69-1	(2R,3R)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-4-oxoazetidin-2-yl acetate
SANFC-005	188396-10-3	allyl 1-((2S,3S)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-4-oxoazetidin-2-yl)-3-methoxy-2-oxocyclohexane-1-carboxylate
SANFC-006	188396-11-4	allyl 1-((2S,3S)-1-(tert-butyldimethylsilyl)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-4-oxoazetidin-2-yl)-3-methoxy-2-oxocyclohexane-1-carboxylate
SANFC-007	-	(3S,4R)-1-(tert-butyldimethylsilyl)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-4-((1R)-3-methoxy-2-oxocyclohexyl)azetidin-2-one
SANFC-008	-	(3S,4R)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-4-((1R)-3-methoxy-2-oxocyclohexyl)azetidin-2-one
SANFC-009	135297-22-2	(3S,4R)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-4-((1R,3S)-3-methoxy-2-oxocyclohexyl)azetidin-2-one
SANFC-010	35249-73-1	benzyl 2-chloro-2-oxoacetate
SANFC-011	181798-22-1	benzyl 2-((2R,3S)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-2-((1R,3S)-3-methoxy-2-oxocyclohexyl)-4-oxoazetidin-1-yl)-2-oxoacetate
SANFC-012	181798-23-2	benzyl (1S,5S,8aS,8bR)-1-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-5-methoxy-2-oxo-1,2,5,6,7,8,8a,8b-octahydroazeto[2,1-a]isoindole-4-carboxylate
SANFC-013	135446-51-4	benzyl (1S,5S,8aS,8bR)-1-((R)-1-hydroxyethyl)-5-methoxy-2-oxo-1,2,5,6,7,8,8a,8b-octahydroazeto[2,1-a]isoindole-4-carboxylate
SANFC-014	69340-58-5	2,2,4a,7,7-pentamethyl-1,2,3,4,4a,5,6,7-octahydro-1,8-naphthyridine
SANFC-015	-	-
SANFC-016	135502-34-0	potassium (1S,5S,8aS,8bR)-1-((R)-1-hydroxyethyl)-5-methoxy-2-oxo-1,2,5,6,7,8,8a,8b-octahydroazeto[2,1-a]isoindole-4-carboxylate
SANFC-017	99464-83-2	1-chloroethyl cyclohexyl carbonate

OptimisedRoute 2Steps 5 · Total yield /

SANFC-00476855-69-1SANFC-008—SANFC-0186651-36-1SANFC-019135297-16-4SANFC-020135413-08-0SANFC-021135297-03-9SANFC-022135297-04-0API · Sanfetrinem cilexetil

Code	CAS No.	Intermediate
SANFC-004	76855-69-1	(2R,3R)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-4-oxoazetidin-2-yl acetate
SANFC-008	-	(3S,4R)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-4-((1R)-3-methoxy-2-oxocyclohexyl)azetidin-2-one
SANFC-018	6651-36-1	(cyclohex-1-en-1-yloxy)trimethylsilane
SANFC-019	135297-16-4	(3S,4R)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-4-((R)-2-oxocyclohexyl)azetidin-2-one
SANFC-020	135413-08-0	N'-((R,E)-2-((2R,3S)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-4-oxoazetidin-2-yl)cyclohexylidene)-4-methylbenzenesulfonohydrazide
SANFC-021	135297-03-9	(3S,4R)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-4-((S)-cyclohex-2-en-1-yl)azetidin-2-one
SANFC-022	135297-04-0	(3S,4R)-4-((1S,2R,6R)-7-oxabicyclo[4.1.0]heptan-2-yl)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)azetidin-2-one

Frequently asked questions

What are the approved indications of Sanfetrinem cilexetil?

Approved indications include: Mycobacterium tuberculosis infection, Pulmonary tuberculosis, Bacterial infection.

When does the Sanfetrinem cilexetil patent expire?

No public expiry year is available for Sanfetrinem cilexetil yet; this page updates once verified.

How many synthesis routes are recorded for Sanfetrinem cilexetil?

2 synthesis routes are recorded; the shortest is 5 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Sanfetrinem cilexetil intermediates?

All intermediates in Sanfetrinem cilexetil routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Sanfetrinem cilexetil intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-05