Zifaxaban
Tier C — Watch / tradeZifaxaban
Targets：F10
Indications (approved)：Venous thrombosis, Pulmonary embolism
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| Zifaxaban | 1378266-98-8 | - |
| ZIFAXA-001 | 540-37-4Available | 4-iodoaniline |
| ZIFAXA-002 | 142-08-5 | pyridin-2(1H)-one |
| ZIFAXA-003 | 13143-47-0 | 1-(4-aminophenyl)pyridin-2(1H)-one |
| ZIFAXA-004 | 161596-47-0Available | (S)-2-(oxiran-2-ylmethyl)isoindoline-1,3-dione |
| ZIFAXA-005 | 1378267-01-6 | (R)-2-(2-hydroxy-3-((4-(2-oxopyridin-1(2H)-yl)phenyl)amino)propyl)isoindoline-1,3-dione |
| ZIFAXA-006 | 1378267-02-7 | (S)-2-((2-oxo-3-(4-(2-oxopyridin-1(2H)-yl)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione |
| ZIFAXA-007 | 1378267-03-8 | (S)-5-(aminomethyl)-3-(4-(2-oxopyridin-1(2H)-yl)phenyl)oxazolidin-2-one hydrochloride |
| ZIFAXA-008 | 42518-98-9Available | 5-chlorothiophene-2-carbonyl chloride |
Frequently asked questions
What are the approved indications of Zifaxaban?
Approved indications include: Venous thrombosis, Pulmonary embolism.
When does the Zifaxaban patent expire?
No public expiry year is available for Zifaxaban yet; this page updates once verified.
How many synthesis routes are recorded for Zifaxaban?
1 synthesis routes are recorded; the shortest is 5 steps with 16 g (Zifaxaban) total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Zifaxaban intermediates?
3 intermediate CAS of Zifaxaban are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Zifaxaban intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-06