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CAS 1276021-71-6

(S)-3-(3,4-diaminophenyl)-1-(4-methoxybenzyl)-4-(4-propoxyphenyl)imidazolidin-2-one

Codes: PQ-912-009

Application context (from source-drug indications)

DementiaVaroglutamstatMild cognitive impairmentVaroglutamstatAlzheimer's diseaseVaroglutamstat

Source drugs (routes using this intermediate)

DrugTierExpiry
VaroglutamstatTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

VaroglutamstatOriginator routesteps: 8total yield: 35 mg
PQ-912→4-propoxybenzaldehyde→1-propoxy-4-vinylbenzene→(S)-tert-butyl (2-hydroxy-1-(4-propoxyphenyl)ethyl)carbamate→(S)-2-((tert-butoxycarbonyl)amino)-2-(4-propoxyphenyl)ethyl 4-methylbenzenesulfonate→(S)-tert-butyl (2-azido-1-(4-propoxyphenyl)ethyl)carbamate→(S)-tert-butyl (2-((4-methoxybenzyl)amino)-1-(4-propoxyphenyl)ethyl)carbamate→(S)-1-(4-methoxybenzyl)-4-(4-propoxyphenyl)imidazolidin-2-one→4-iodobenzene-1,2-diamine→(S)-3-(3,4-diaminophenyl)-1-(4-methoxybenzyl)-4-(4-propoxyphenyl)imidazolidin-2-one

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