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CAS 2102395-60-6
N4-(5-fluoropyrimidin-2-yl)-2-methylpyridine-3,4-diamine
Codes: JNJ-54175446-004
Application context (from source-drug indications)
Major depressive disorderJNJ-54175446Inflammatory diseaseJNJ-54175446
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| JNJ-54175446 | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-chloro-2-methyl-3-nitropyridine→5-fluoropyrimidin-2-amine→5-fluoro-N-(2-methyl-3-nitropyridin-4-yl)pyrimidin-2-amine→N4-(5-fluoropyrimidin-2-yl)-2-methylpyridine-3,4-diamine→1-(5-fluoropyrimidin-2-yl)-4-methyl-1H-[1,2,3]triazolo[4,5-c]pyridine→1-(5-fluoropyrimidin-2-yl)-4-methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine→2-chloro-3-(trifluoromethyl)benzoic acid→(2-chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyrimidin-2-yl)-4-methyl-1,4,6,7-tetrahydro-5H-[1,2,3]triazolo[4,5-c]pyridin-5-yl)methanone
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