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CAS 341970-89-6
methyl (3aS,4R,11bR)-4-(2-(1,3-dioxolan-2-yl)-4-methoxybutyl)-3-((R)-1-(naphthalen-1-yl)ethyl)-2,3,3a,4,5,7-hexahydro-1H-pyrrolo[2,3-d]carbazole-6-carboxylate
Codes: 18-MC-003
Application context (from source-drug indications)
利什曼原虫感染18-MethoxycoronaridineDrug-related adverse effects and reactions18-MethoxycoronaridineOpioid dependence18-Methoxycoronaridine
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 18-Methoxycoronaridine | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
methyl 3-((R)-1-(naphthalen-1-yl)ethyl)-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole-5-carboxylate→4-(1,3-dioxolan-2-yl)-6-methoxyhexanal→methyl (3aS,4R,11bR)-4-(2-(1,3-dioxolan-2-yl)-4-methoxybutyl)-3-((R)-1-(naphthalen-1-yl)ethyl)-2,3,3a,4,5,7-hexahydro-1H-pyrrolo[2,3-d]carbazole-6-carboxylate→methyl (3aR,4S,11bS)-4-(2-(1,3-dioxolan-2-yl)-4-methoxybutyl)-3-((R)-1-(naphthalen-1-yl)ethyl)-2,3,3a,4,5,7-hexahydro-1H-pyrrolo[2,3-d]carbazole-6-carboxylate→methyl 5-(2-(1,3-dioxolan-2-yl)-4-methoxybutyl)-3-((R)-1-(naphthalen-1-yl)ethyl)-1,2,3,4,5,6,7,8-octahydroazonino[5,4-b]indole-7-carboxylate→methyl (5R,7R)-5-(2-(1,3-dioxolan-2-yl)-4-methoxybutyl)-1,2,3,4,5,6,7,8-octahydroazonino[5,4-b]indole-7-carboxylate→methyl (7S,9R)-5-(2-methoxyethyl)-1,6,7,8,9,10-hexahydro-2H-3,7-methano[1]azacycloundecino[5,4-b]indole-9-carboxylate
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