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CAS 476475-44-2
methyl 4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxylate
Codes: GALU-009
Application context (from source-drug indications)
Amyotrophic lateral sclerosisGalunisertibPeritoneal cancerGalunisertibNasopharyngeal carcinomaGalunisertibColorectal cancerGalunisertibProstate cancerGalunisertibRectal cancerGalunisertib
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Galunisertib | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-bromoaniline→but-3-en-2-one→6-bromo-4-methylquinoline→methyl 6-methylpicolinate→2-(6-bromoquinolin-4-yl)-1-(6-methylpyridin-2-yl)ethan-1-one→1-aminopyrrolidin-2-one hydrochloride→(Z)-1-((2-(6-bromoquinolin-4-yl)-1-(6-methylpyridin-2-yl)ethylidene)amino)pyrrolidin-2-one→6-bromo-4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline→methyl 4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxylate
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