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CAS 866395-21-3
benzyl (R)-(4-hydroxybutan-2-yl)carbamate
Codes: Tibremciclib-002
Application context (from source-drug indications)
Breast cancerTibremciclib TartrateMetastatic breast cancerTibremciclib TartrateSolid tumourTibremciclib Tartrate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Tibremciclib Tartrate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(R)-3-aminobutan-1-ol→benzyl (R)-(4-hydroxybutan-2-yl)carbamate→benzyl (R)-(4-oxobutan-2-yl)carbamate→methyl 2-(dimethoxyphosphoryl)acetate→methyl (R,E)-5-(((benzyloxy)carbonyl)amino)hex-2-enoate→(R)-6-methylpiperidin-2-one
Intermediates available on this site
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