CAS 372-31-6

ethyl 4,4,4-trifluoro-3-oxobutanoate

Codes: BPN-14770-004

Application context (from source-drug indications)

脆性X染色体综合征Zatolmilast乔丹综合征ZatolmilastHepatic function declineZatolmilastRenal impairmentZatolmilastAlzheimer's diseaseZatolmilastDepressionZatolmilast

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Zatolmilast	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

ZatolmilastOriginator routesteps: 5total yield: 0.042 g

3-chlorobenzonitrile→ethyl 3-chlorobenzimidate hydrochloride→3-chlorobenzimidamide→ethyl 4,4,4-trifluoro-3-oxobutanoate→2-(3-chlorophenyl)-6-(trifluoromethyl)pyrimidin-4(3H)-one→4-chloro-2-(3-chlorophenyl)-6-(trifluoromethyl)pyrimidine→2-(4-aminophenyl)acetamide→BPN-14770

Intermediates available on this site

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